CHAPTER ONE 1.1 INTRODUCTION Plants have provided a source of inspiration for novel drug compounds, as plant derived medicines have made large contributions to human health and wellbeing. Plant extracts have been used for a wide variety of purposes for many thousands of years (Jones, 1996). The antimicrobial activity of plant oils and extracts has formed the basis of many applications, including raw and processed food preservatives, pharmaceuticals, alternative medicine and natural therapies ...
ABSTRACT Erythromycin is antibioticsproduced from a strain of Streptomyces erythreus (later changed to "Saccharopolysporaerythraea") which belongs to the group of macrolides which tends toinhibit the growth/development of bacteria. It sometimes exhibits bactericidalcharacteristics when administered in high concentration. It carries out itsbacteriostatic actions by binding to the 23s RNA component of the 50s ribosomeof the bacteria, thereby interfering with the assembly of the 50s subun...
