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Anti-Infl ammatory Dietary Combo in Overweight and Obese Women with Polycystic Ovary Syndrome

Abstract
Background: Polycystic ovary syndrome (PCOS) is of clinical and public health importance, affecting up to one in fi ve women of reproductive
age. It has signifi cant and diverse clinical implications including reproductive, metabolic, and psychological features. Aim: The study was to
investigate the effect of anti-infl ammatory dietary combo on metabolic, endocrine, infl ammatory, and reproductive profi les in overweight
and obese women with PCOS. Materials and Methods: A total of 100 nonpregnant, overweight, and obese adult females with PCOS
according to the Rotterdam criteria, were screened during the year 2012, and 75 completed the trial. At baseline and study end, fasting blood
samples were drawn to measure biological markers, body fat percent (BFP), and visceral fat area (VFA) were assessed by the InBody720
device and anthropometric measurements were done for all participants who were subjected to an anti-infl ammatory hypocaloric diet and
physical activity for 12 weeks. Results: At study completion, we achieved moderate weight loss of (± 7%) and signifi cant improvements
in body composition, hormones and menstrual cyclicity, blood pressure, glucose homeostasis, dyslipidemia, C-reactive protein (CRP), and
serum amyloid A (SAA) (surrogate measures of cardiovascular risk (CVR)). This was a clinically relevant weight loss that is associated with
a reduced prevalence of type 2 diabetes mellitus (DM2) and metabolic syndrome (MS) in the general population and improved fertility
outcomes in PCOS. We achieved 63% regain of menstrual cyclicity and 12% spontaneous pregnancy rate within 12 week. Conclusions:
We have explored an additional dietary treatment option with good prognostic metabolic and reproductive responses to weight loss that
occur in overweight and obese PCOS.
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APA

LTrYQZ75c00124f4b55a0.26199105, Y. (2018). Anti-Infl ammatory Dietary Combo in Overweight and Obese Women with Polycystic Ovary Syndrome. Afribary. Retrieved from https://beta.afribary.com/works/anti-infl-ammatory-dietary-combo-in-overweight-and-obese-women-with-polycystic-ovary-syndrome-7422

MLA 8th

LTrYQZ75c00124f4b55a0.26199105, YNNu8Io5c00124f4aad32.32260851 "Anti-Infl ammatory Dietary Combo in Overweight and Obese Women with Polycystic Ovary Syndrome" Afribary. Afribary, 29 Jan. 2018, https://beta.afribary.com/works/anti-infl-ammatory-dietary-combo-in-overweight-and-obese-women-with-polycystic-ovary-syndrome-7422. Accessed 24 Apr. 2025.

MLA7

LTrYQZ75c00124f4b55a0.26199105, YNNu8Io5c00124f4aad32.32260851 . "Anti-Infl ammatory Dietary Combo in Overweight and Obese Women with Polycystic Ovary Syndrome". Afribary, Afribary, 29 Jan. 2018. Web. 24 Apr. 2025. < https://beta.afribary.com/works/anti-infl-ammatory-dietary-combo-in-overweight-and-obese-women-with-polycystic-ovary-syndrome-7422 >.

Chicago

LTrYQZ75c00124f4b55a0.26199105, YNNu8Io5c00124f4aad32.32260851 . "Anti-Infl ammatory Dietary Combo in Overweight and Obese Women with Polycystic Ovary Syndrome" Afribary (2018). Accessed April 24, 2025. https://beta.afribary.com/works/anti-infl-ammatory-dietary-combo-in-overweight-and-obese-women-with-polycystic-ovary-syndrome-7422

Document Details
By: YNNu8Io5c00124f4aad32.32260851 LTrYQZ75c00124f4b55a0.26199105 Field: Human Nutrition Type: Thesis 7 PAGES (3000 WORDS) (pdf)
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